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Delta-9-Tetrahydrocannabinolic Acid

  • Acronym: ∆9-THCA
  • Class: delta_9_tetrahydrocannabinol
  • Formula: C22H30O4
  • Molecular Weight.: 358.478 g/mol
  • Boiling Point: 105º
  • CAS: 23978-85-0

Tetrahydrocannabinolic acid, known by its acronym THCA or ∆9-THCA, is the acid precursor of ∆9-THC or THC and is a non-psychotropic phytocannabinoid found mostly in the fresh plant. THCA is biosynthesized from the enzymatic action of THCA-synthase on Cannabigerolic Acid (CBGA).

It is estimated that approximately 70% of the THCA content will be converted to THC upon a chemical reaction called decarboxylation in which the carboxyl group is eliminated. Decarboxylation occurs naturally in the plant in low proportion during its flowering cycle. But this THCA transformation process can also be induced and accelerated by exposing dry plant matter to alkaline conditions, UV rays and/or high temperatures (especially when burning or vaporizing), obtaining THC that is more easily assimilated by the organism.